Dr. Appendino is a Professor of Organic Chemistry at the Università del Piemonte Orientale, Department of Pharmaceutical Sciences, Novara (Italy), since 2000. Research activity in his laboratories takes inspiration from plant natural products to address problems in various realms of biomedical investigation, from pharmacology and nutrition (new drug leads and health-promoting dietary ingredients) to organic/medicinal chemistry (new synthetic methodologies and optimization of natural product drug leads) and cell biology (novel mechanisms of action). Author of over 350 peer-reviewed articles and 15 book chapters on the chemistry and bioactivity of plant natural products. Editor-in-Chief of the journal Fitoterapia and member of the Advisory Board of the PharmaNutrition, Natural Products Reports, Acta Pharmaceutica Sinica B, and Progress in the Chemistry of Organic Natural Products. Recipient of the Rhône-Poulenc Rorer Award of the Phytochemical Society of Europe (1991), the Medaglia Quilico of the Società Chimica Italiana (2009) and the Bruker Prize of the Phytochemical Society of Europe in 2014 for his studies on bioactive natural products.